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Updated: Jun 14, 2025

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
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A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

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胎儿基因调节基因删除与精神分裂症的认知能力低下和皮质形态变化以及基于社区的样本有关

Jennifer K Forsyth, Jinhan Zhu, Ariana S Chavannes

    medRxiv : the preprint server for health sciences
    |August 30, 2024
    PubMed
    概括

    与精神分裂症谱系障碍 (SSD) 相关的副本数变异 (CNV) 影响认知和发育的可变性. 胎儿基因调节中的删除会影响智力功能和大脑结构,建议个性化治疗途径.

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    The Use of Trace Eyeblink Classical Conditioning to Assess Hippocampal Dysfunction in a Rat Model of Fetal Alcohol Spectrum Disorders

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    Biological Causes of Schizophrenia01:29

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    Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
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