在土耳其的伤寒肠道穿孔
1Dokuz Eylul University, Internal Medicine Department, Izmir, Türkiye.
Kathmandu University medical journal (KUMJ)
|August 30, 2024
概括
伤寒热可以导致肠道穿孔,这是一个严重的并发症. 早期诊断和及时的医疗/外科治疗,以及重症监护,对于拯救生命和减少诸如孔等并发症至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
- 手术病理学手术病理学
背景情况:
- 伤寒热是一种由沙门氏菌Typhi引起的全身性感染,具有重大风险.
- 肠道穿孔是一种严重的并发症,源于末端大肠炎症.
研究的目的:
- 分析3个肠道穿孔病例的临床和实验室发现,在伤寒流行期间.
- 评估伤寒引起的肠道穿孔患者的治疗结果和随访.
主要方法:
- 在伤寒流行期间,对三名年轻男性患者 (20-22岁) 的案例研究分析.
- 对临床表现 (发烧,不适,食欲丧失),实验室结果 (白细胞瘤,高胺酶,格鲁伯-维达尔测试) 和身体发现 (肝壮病,腹部疼痛) 的审查.
- 评估治疗策略,包括医疗管理,手术干预 (初级修复或切除和解剖) 和重症监护.
主要成果:
- 所有患者都出现了发烧,不适和食欲丧失.
- 临床发现包括肝扩大 (2例) 和腹部疼痛 (3例).
- 实验室检测显示白细胞症,血清中氨基酶的升高,和积极的格鲁伯-维达尔聚合在所有情况下.
- 早期诊断和联合医疗外科干预与重症监护显著降低死亡率和发病率.
结论:
- 早期诊断和及时的多学科治疗对于管理与伤寒有关的肠道穿孔至关重要.
- 积极的重症监护和手术干预是拯救生命的措施.
- 即使在医疗治疗期间,对潜在的反孔效应保持警至关重要.
相关概念视频
Esophageal Perforation-I: Introduction
76
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
76
Esophageal Perforation-II: Clinical Manifestations and Management
53
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
53
Inflammatory Bowel Disease I: Ulcerative Colitis
159
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
159
Appendicitis-I: Introduction
99
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
99
Inflammatory Bowel Disease II: Crohn's Disease
205
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
205
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
111
Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
111


