盐水清洗可以预防通过直肠前列腺活检后的感染性并发症:一项随机前性研究
Taha Çetin1, Mehmet Yiğit Yalçın2, Mert Hamza Özbilen3
1Urology Department, University of Health Sciences, Izmir Bozyaka Training and Research Hospital, Izmir, Turkey.
Urologia
|August 30, 2024
概括
盐水直肠灌与消毒剂解决方案一样有效,用于预防经过直肠前列腺活检 (TRUS-PB) 后的感染. 这种具有成本效益的方法提供了一个可行的替代方案,特别是对于抗菌素过敏的患者.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 预防传染病 预防传染病
- 医疗程序 医疗程序
背景情况:
- 跨直肠前列腺活检 (TRUS-PB) 是诊断前列腺癌的常见程序.
- 感染是TRUS-PB后的一个重要并发症,通常通过抗生素预防和直肠制备来管理.
- 特定的直肠清洁剂在预防活检后感染中的作用需要进一步研究.
研究的目的:
- 为了比较消毒溶液与机械直肠灌用盐水在TRUS-PB后减少感染率的疗效.
- 评估不同直肠制备方法对感染并发症和患者结局的影响.
主要方法:
- 一项随机对照试验与接受TRUS-PB.患者进行.
- 患者接受了标准的抗生素预防,并根据直肠灌策略随机分为三组.
- 感染率,发烧发病率和病理结果在各组之间进行了比较.
主要成果:
- 两组之间感染率 (p=0.780) 或发烧发病率 (p=0.776) 没有显著差异.
- 整体并发症率很低 (4%).
- 在所有灌策略中,病理分析结果是可比的 (p=0.764).
结论:
- 用盐水进行机械直肠清洁,在预防TRUS-PB后感染方面,与防腐剂一样有效.
- 盐水为直肠制备提供了一个具有成本效益和无副作用的替代方案.
- 研究结果表明,从强制使用消毒剂转向机械清洗,特别是对于过敏患者来说,可能会出现转变.
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