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在MRI指导的前列腺癌聚焦超声波期间,用于预测除区域的程序内扩散加权成像
Rachel R Bitton1, Wei Shao1, Yosef Chodakeiwitz1
1From the Departments of Radiology (R.R.B., Y.C., R.L.B., M.R., P.G.) and Urology (G.S.), Stanford University School of Medicine, 1024 Welch Rd, MC 5488, Stanford, CA 94305; and Department of Medical Quantitative Health, University of Florida, Gainesville, Fla (W.S.).
Radiology. Imaging cancer
|August 30, 2024
概括
扩散权重成像 (DWI) 能够更好地预测前列腺癌消化边缘,而不是在MRI引导的聚焦超声波后的热剂量测量. DWI直接可视化了切除区域,提供了强大的非对比方法来预测治疗成功.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 前列腺癌的治疗通常涉及切除.
- 准确预测除边际对于治疗疗效至关重要.
- 非对比成像方法是可取的,以避免潜在的并发症.
研究的目的:
- 将扩散权重成像 (DWI) 与热剂量计进行比较,以预测用MRI指导聚焦超声波 (MRgFUS) 治疗的前列腺癌的消化边缘.
- 为了评估DWI和热剂量计的准确性,与对比度增强的参考标准对比.
主要方法:
- 一项前性试验的二次分析 (NCT01657942) 包括17名参与者接受了为前列腺癌治疗的MRgFUS治疗.
- 来自热剂量计和DWI的废除轮与治疗后对比度增强的非透体积 (NPV) 轮进行了比较.
- 量化分析使用了子相似系数 (DSC) 和平均豪斯多夫距离 (mHD).
主要成果:
- 酒后驾驶 (DWI) 显示在切除边缘有一个超强的边缘.
- DWI轮 (平均DSC = 0.84) 与NPV参考标准相比,热剂量轮 (平均DSC = 0.64) 更好地匹配了NPV参考标准.
- 与DWI和NPV成像相比,热剂量轮低估了切除区域.
结论:
- DWI是一种有前途的非对比方法,用于预测前列腺癌MRgFUS后的切除边缘.
- DWI直接可视化了切除区域,并且对移动文物具有强大性能.
- DWI与参考标准NPV的相关性比热剂量计更好.
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