甲状腺激素相关的蛋白质介导高血症由于转移性状细胞癌起源于pilonidal疾病:一个案例报告
Annalisa Montebello1, Martina Grech2, Nicoletta Maniscalco2
1Department of Diabetes and Endocrinology, Mater Dei Hospital, Birkirkara, Malta.
British journal of hospital medicine (London, England : 2005)
|August 30, 2024
概括
在最初的错误诊断后,在一名56岁的男性中诊断出了一种罕见的先进的出生裂皮肤状细胞癌,这是一种罕见的病例. 尽管进行了多式治疗,但这种侵袭性癌症导致了广泛的转移和息治疗.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 癌症研究 癌症研究
背景情况:
- 状细胞癌 (SCC) 是一种常见的皮肤癌,但出生裂的SCC很少见.
- 柱状是出生裂中常见的疾病,通常需要手术干预.
- 经过广泛转移的先进的SCC带来了重大治疗挑战.
研究的目的:
- 报告一个罕见的先进状细胞癌的出生裂皮的罕见病例.
- 讨论这种罕见恶性瘤的诊断挑战和治疗方法.
- 为了突出该地区晚期SCC的攻击性和不良预后.
主要方法:
- 一个56岁的男性患者的病例报告.
- 对临床表现,诊断工作和治疗过程的审查.
- 多模式治疗包括手术,放射治疗,化疗 (cisplatin) 和免疫治疗 (cemiplimab).
主要成果:
- 诊断IVb期状细胞癌的出生裂皮肤与双边 inguinal 淋巴结转移和皮下转移沉积.
- 最初的错误诊断是柱状.
- 疾病进展尽管有积极的多式疗法,包括严重的恶性性高血病 (HHM).
结论:
- 出生的皮肤裂的状细胞癌是一种罕见但具有攻击性的恶性瘤.
- 早期和准确的诊断至关重要,尽管具有挑战性.
- 多模式治疗可能是必要的,但在晚期,预后仍然很差.
- 息治疗对于晚期病例的症状管理至关重要.
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