英国高后果传染病住院患者的临床管理
Alejandra Alonso1, Jonathan Cohen1, Joby Cole1
1Alejandra Alonso, MPH, is a Consultant in Paediatric Infectious Diseases, Department of Infection, Evelina London Children's Hospital; Jonathan Cohen, PhD, is a Consultant in Paediatric Immunology and Infectious Diseases, Department of Paediatric Immunology and Infectious Diseases, Evelina London Children's Hospital; Chris Meadows, FRCP, is a Consultant in Intensive Care Medicine and ECMO, Department of Critical Care, St Thomas' Hospital; and Geraldine O'Hara, PhD, is a Consultant in Infectious Diseases, Department of Infectious Diseases, St Thomas' Hospital; all with Guy's and St Thomas' NHS Foundation Trust, London. Jonathan Cohen is also a Consultant, Department of Women and Children's Health, and Chris Meadows is also an Honorary Senior Lecturer, Faculty of Life Sciences and Medicine; both at St Thomas Hospital, Kings College London, London. Joby Cole, PhD, is a Consultant in Infectious Diseases and Acute Medicine, and Anne J. Tunbridge, FRCP, is a Consultant in Infectious Diseases; both in the Department of Infection and Tropical Medicine, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield. Marieke Emonts, PhD, and Stephen Owens, PhD, are Consultants in Paediatric Infectious Diseases, Department of Paediatric Immunology and Infectious Diseases, Great North Children's Hospital; Brendan A. I. Payne, PhD, is a Consultant in Infectious Diseases and Virology, and Matthias L. Schmid, MD, is a Consultant in Infectious Diseases, Department of Infection and Tropical Medicine, Royal Victoria Infirmary; all with the Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne. Marieke Emonts is also an Honorary Professor, Paediatric Infectious Diseases, and Brendan A. I. Payne is also an Honorary Clinical Senior Lecturer; both at the Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne. Natasha Karunaharan, MRCPath, is a Consultant in Infectious Diseases and Microbiology, and Jake Dunning, PhD, is a Consultant in Infectious Diseases; both in the Department of Infectious Diseases, Royal Free Hospital, Royal Free London NHS Foundation Trust, London. Jake Dunning is also a Senior Research Fellow, Pandemic Sciences Institute, University of Oxford, Oxford. David Porter, PhD, and Andrew Riordan, FRCPCH, are Consultants in Paediatric Infectious Diseases and Immunology, Department of Paediatric Infectious Diseases and Immunology, Alder Hey Children's Hospital, Alder Hey Children's NHS Foundation Trust, Liverpool. Libuse Ratcliffe, FRCP, is a Consultant in Infectious Diseases, and Mike Beadsworth, MD, is a Consultant in Infectious Diseases and Tropical Medicine; both in the Tropical and Infectious Diseases Unit, Royal Liverpool Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool. Ruchi Sinha, MRCPCH, is a Consultant Paediatric Intensivist, Children's Intensive Care, and Elizabeth Whittaker, PhD, is a Consultant in Paediatric Infectious Disease and Immunology, Children's Infectious Diseases; both at St Mary's Hospital, Imperial College Healthcare NHS Trust, London. Elizabeth Whittaker is also an Honorary Senior Clinical Lecturer, Section of Paediatric Infectious Diseases, Imperial College, London.
自1971年以来,英格兰加强了其高后果传染病 (HCID) 应对系统,建立了针对病毒性出血热和其他危险病原体的专门治疗中心. 这个系统对于管理埃博拉和COVID-19等疫情至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 自1971年以来,英格兰一直在管理病毒性出血热,并提供专业隔离设施.
- 最近的疫情 (MERS,H7N9,埃博拉) 促使加强对高后果传染病 (HCID) 的准备.
- 在英国,HCID计划 (2016-2018) 增强了临床和公共卫生响应途径.
研究的目的:
- 描述英格兰空中和联系HCID治疗中心网络的形成和结构.
- 概述英国HCID患者安全有效的临床管理方法.
- 确定英格兰HCID管理的未来挑战.
主要方法:
- 对英格兰HCID准备和应对情况的案例研究分析.
- 审查HCID计划的实施和成果.
- 描述空中和接触HCID治疗中心的结构和功能.
主要成果:
- 英国已经建立了强大的HCID管理途径和治疗中心,包括专门的空中和接触设施.
- 这些通路被激活用于MERS,mopox,禽流感,拉萨热病和早期COVID-19病例.
- 该网络包括高级隔离单位和新建的空中HCID治疗中心.
结论:
- 英格兰拥有完善的管理高危传染病的系统.
- HCID治疗中心网络提供安全有效的患者护理.
- 为了应对HCID管理的未来挑战,需要进行持续的评估和适应.
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