事件高血压持续时间与老年人的认知表现之间的关联:来自NHANES 2011-2014年的数据
Chunlei Liu1,2, Qi Li1,2, Zhuqing Li2
1School of Medicine, Nankai University, Tianjin, 300071, China.
Aging clinical and experimental research
|August 30, 2024
概括
较长的高血压持续时间与更差的认知表现有关,特别是在中年人群中. 这项研究强调了高血压持续时间对认知健康的影响.
科学领域:
- 老年学与公共卫生
- 神经科学与衰老问题
背景情况:
- 高血压是认知障碍的一个已知的危险因素.
- 高血压持续时间对认知能力下降的具体影响尚不清楚.
研究的目的:
- 调查高血压持续时间和老年人认知表现之间的关联.
- 使用来自国家健康和营养检查调查 (2011-2014) 的数据.
主要方法:
- 用物流回归分析来评估这种关系.
- 限制立方线 (RCS) 分析用于探索非线性关联.
- 用数字符号替代测试 (DSST) 和动物流利性测试 (AFT) 等测试来评估认知表现.
主要成果:
- 高血压持续时间的增加与DSST和AFT中认知障碍的风险更高相关.
- RCS分析表明,在DSST中,高血压持续时间和认知障碍风险之间存在线性关联.
- 亚组分析显示,DSST和CERAD对中年高血压 (诊断年龄<55岁) 有线关联.
结论:
- 长时间接触高血压会对认知功能产生负面影响.
- 患有高血压的中年人对认知衰退的特别脆弱,疾病持续时间较长.
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