在健康的高加索人群中,辐射周周毛囊毛细管的血管密度规范数据
Rita Serra1,2,3, Antonio Pinna4, Andrea Angius5
1Institute of Genetic and Biomedical Research, National Research Council, C/O S.S 554 Bivio Per Sestu Km 4,500. Cittadella Universitaria Di Cagliari. Monserrato, 09042, Cagliari, Italy. rita.serra@ymail.com.
概括
在健康的高加索成年人中,随着年龄的增长,辐射周周毛细管 (RPC) 中的血管密度 (VD) 降低. 这项研究确定了RPC的规范性VD值,这对于临床应用至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 神经科学是一个神经科学.
- 医疗成像医学成像
背景情况:
- 辐射周毛细血管 (RPC) 对于视神经头部 (ONH) 的健康至关重要.
- 在RPC血管密度 (VD) 的早期变化可以表明视神经和视网膜疾病.
- 建立规范性VD值对于疾病检测至关重要.
研究的目的:
- 在健康的高加索人群中创建RPC血管密度 (VD) 的规范数据库.
- 调查年龄和性别对RPC VD的影响.
主要方法:
- 633名健康的白人受试者接受了全面的眼科检查.
- 面对面的光学连贯性断层扫描血管造影 (OCTA) 用于捕捉RPC复合体扫描.
- AngioAnalyticsTM软件计算了RPC VD,用线性混合模型分析了年龄和性别影响.
主要成果:
- 560名受试者符合纳入标准,分层分成年龄组.
- 平均RPC VD为53.03±4.27%. 这是一个很好的结果.
- 随着年龄的增长,RPC VD显著下降 (r = -0.454,p < 0.0001),每年下降0.12%. 没有观察到明显的性别差异.
结论:
- 在健康的高加索人中,RPC VD 随着年龄的增长而减少.
- 建立的规范性数据可以帮助临床评估视神经健康状况.
- 随着年龄的增长,RPC VD 的下降是未来诊断工具的一个关键发现.
相关概念视频
01:11Assessment of radial pulse
808
Assessment of Radial Pulse
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:
808
01:16Pulse
473
When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...
The pulse serves as a clinical...
473
01:27Assessment of the Cardiovascular System III: Palpation
251
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
251
01:20Vascular Resistance
3.6K
Vascular resistance is a critical concept in understanding blood flow dynamics in the circulatory system. It refers to the resistance that blood encounters as it flows through the blood vessels. This resistance is a key factor in determining blood pressure and cardiac workload.
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
3.6K