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计算机断层扫描中的视觉神经外直径反映了骨突症患者内压力升高的情况
Dominic J Romeo1, Jonathan H Sussman1, Benjamin B Massenburg1
1From the Divisions of Plastic, Reconstructive, and Oral Surgery.
Plastic and reconstructive surgery
|August 30, 2024
概括
在CT扫描上,视神经外直径 (ONSD) 可以帮助检测内压力升高 (ICP) 在内静止病患者. 将ONSD与患者年龄相结合,可以提高临床决策的准确性.
科学领域:
- 神经外科 神经外科
- 放射学 放射学是一门学科.
- 眼科医生 眼科 眼科
背景情况:
- 内压升高 (ICP) 的评估对于内的治疗决策至关重要.
- 非侵入性的ICP测量技术是有限的.
- 这项研究研究了低剂量CT扫描上的视觉神经外直径 (ONSD) 作为潜在的ICP指标.
研究的目的:
- 评估小儿关节缩症患者的低剂量CT扫描测量的ONSD与ICP之间的关联.
- 为了确定ONSD的诊断准确性,提高ICP.
- 探索ONSD作为一个非侵入性的ICP代理程序的实用性.
主要方法:
- 对132名受ICP监测的小儿科骨突症患者进行了回顾性分析.
- 在手术前的CT扫描中测量出的ONSD是由一个蒙面神经放射科医生进行的.
- 将ONSD与直接的手术内ICP测量和光谱域光学连贯断层扫描 (SD-OCT) 数据进行比较.
主要成果:
- 在ICP≥15 mmHg和≥20 mmHg的患者中,最大的ONSD显著增加.
- ONSD测量 (最大,最小,平均) 显示与直接ICP有显著的相关性.
- 5.75毫米的ONSD最大值为ICP≥15mmHg提供了65%的灵敏度和64%的特异性.
- 使用ONSD max和age的算法实现了64%的灵敏度和80%的特异性,用于ICP≥20 mmHg.
结论:
- 在低剂量CT扫描上进行的ONSD测量在检测升高的ICP时提供了适度的准确性.
- 纳入患者年龄可以提高ONSD用于ICP检测的精度.
- ONSD可以作为一个有价值的,可访问的ICP代理,用于骨突症管理的临床指导.
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