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Updated: Jun 14, 2025

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在PARP9中,PARP9通过TGF-β/Smad轴和pirfenidone影响心肌功能

Nannan Chen1, Lianzhi Zhang1, Zhang Zhong1

  • 1Department of Cardiology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China.

Biomolecules & biomedicine
|August 30, 2024
PubMed
概括

皮尔费尼 (PFD) 通过调节多 (ADP-ribose) 聚合酶9 (PARP9) 和TGF-β/Smad通路,有效降低安吉奥素II诱导的心脏纤维细胞激活和纤维化,为心肌纤维化提供潜在的治疗方法.

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