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空气污染物度对中国四川甲型和乙型流感的不同影响

Zhirui Li¹, Lijun Zhou¹, Qian Zhang²

¹Department of Disease Control and Prevention, Sichuan provincial Center for Disease Control and Prevention, Chengdu, Sichuan 610000, PR China.

Ecotoxicology and environmental safety

|August 30, 2024

概括

空气污染,特别是二氧化硫和颗粒物,增加了流感A感染的风险. 一些污染物降低了B型流感的风险,这表明对不同流感亚型的影响不同.

科学领域:

环境健康环境健康
流行病学流行病学
传染性疾病传染性疾病

背景情况:

空气污染对呼吸系统健康构成重大风险.
之前的研究将空气污染物与流感类疾病访问的增加联系起来.
对空气污染对流感亚型的影响差异的研究是有限的.

研究的目的:

调查中国四川省空气污染物度与不同流感亚型之间的相关性.
分析各种空气污染物如何影响流感A和流感B的发病率.
探索空气污染对流感感染影响的子组变化.

主要方法:

利用通用添加剂和分布式滞后非线性模型来分析来自30家医院 (2017-2019) 的每日流感数据.
评估了每日空气污染物水平 (PM2.5,SO2,CO,NO2,PM10) 和流感亚型之间的关联.
根据性别,年龄和地理位置进行分组分析,以完善影响评估.

主要成果:

在各种滞后日暴露于PM2.5,SO2,CO和NO2时,A型流感风险显著增加.
在不同的滞后日,B型流感风险与PM10,SO2,PM2.5和CO暴露的相关性降低.
确定了17462个阳性流感标本;12607个是流感A,4855个是流感B.

结论:

空气污染物度对流感A和B有不一致的影响,而流感A更容易受到影响.
降低SO2,CO,NO2和PM2.5的水平可以降低A型流感的发生率.
了解污染物对特定流感亚型的影响有助于预测季节性趋势和制定控制策略.

关键词:

空气污染大气污染气体空气污染物气体空气污染物流感是一次流感.颗粒物质颗粒物质是什么

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