不同的血小板丰富的纤维素中心流离协议是否会在提取地点增强新骨的形成?
Toghrul Aliyev1, Murat Ulu2, Xhini Rizaj3
1Professor, Faculty of Dentistry, Oral and Maxillofacial Department, Azerbaijan Medical University, Baku, Azerbaijan.
概括
富含血小板纤维素 (PRF) 在拔牙后显著增强新的骨形成. 与高级PRF (A-PRF) 和自然愈合相比,富含白细胞纤维素 (L-PRF) 显示出最实质性的骨再生.
科学领域:
- 牙科植入物学 牙科植入物学
- 再生医学是一种再生医学.
- 生物材料是一种生物材料.
背景情况:
- 防止骨质再吸收对于牙植入成功至关重要.
- 骨再生的临床方案是有效的牙置换所需要的.
研究的目的:
- 评估不同丰富血小板纤维素 (PRF) 协议对新骨形成的疗效.
- 评估PRF对骨再生标志物和临床愈合结果的影响.
主要方法:
- 一项随机临床试验,涉及57名接受前牙切除的患者.
- 富含白细胞纤维素 (L-PRF),高级PRF (A-PRF) 和对照组 (自然愈合) 的比较.
- 在提取8周后,对新骨形成的基因组学分析和再生标志物的免疫基因化学评估.
主要成果:
- 与对照组 (32.68%) 相比,L-PRF和A-PRF组的新骨形成显著增加 (分别为70.74%和61.37%).
- 在PRF组中观察到骨质素,性酸酶和增殖细胞核抗原的表达增加.
- 与对照组相比,PRF组表现出减少疼痛,胀和改善愈合.
结论:
- 富含血小板纤维素 (PRF) 有效地促进骨再生,增强拔牙后的愈合.
- 富含白细胞纤维素 (L-PRF) 似乎是最大限度地促进骨形成的最有效的PRF协议.
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