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鱼类中的毒性:当前的视角

Md Helal Uddin1, Jinnath Rehana Ritu1, Sravan Kumar Putnala2

  • 1Department of Biology, University of Saskatchewan, Saskatoon, SK, S7N 5E2, Canada; Department of Fisheries Management, Bangladesh Agricultural University, Mymensingh, 2202, Bangladesh.

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人类活动释放 (Se),一种对鱼类有毒的金属化物,导致氧化损伤,发育问题和神经毒性. 这篇评论详细介绍了Se Se的细节.

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科学领域:

  • 环境毒理学环境毒理学
  • 水生生态毒理学 水生生态毒理学
  • 鱼类生理学 鱼类生理学

背景情况:

  • 人类活动,包括采矿和化石燃料的燃烧,释放 (Se),一个金属化污染物进入水生生态系统.
  • 在微量中是必不可少的,但在高度下生物累积并变得有毒,对水生生物,特别是鱼类构成风险.
  • 鱼类是水生食物网的重要组成部分和人类重要的蛋白质来源,使Se积累成为一个关键的生态和食品安全问题.

研究的目的:

  • 为鱼类暴露 (Se) 的不良生理影响提供最新和深入的分析.
  • 为未来的研究方向确定关于Se对鱼类健康和水生生态系统的影响的知识差距.

主要方法:

  • 对现有关于鱼类毒性研究的综合文献综述.
  • 细胞机制的分析,包括氧化应激途径 (ROS 生产与抗氧化能力).
  • 评估对各种生理功能的影响:新陈代谢,生长,繁殖,发育和神经行为反应.

主要成果:

  • 通过破坏氧化还原平衡,诱导细胞水平的毒性,导致氧化损伤.
  • 长期暴露于Se会损害鱼类的关键生理功能,包括新陈代谢,生长和繁殖.
  • 作为一种强大的原体,通过母体转移到卵子引起发育异常,并具有跨代持续性. 神经毒性是由脑中Se诱导的氧化应激驱动的,影响认知,行为和社会互动.

结论:

  • 来自人为来源的高含量对鱼类健康构成重大威胁,影响多个生理系统和行为.
  • 了解Se毒性的全部程度,包括其发育和神经毒性影响,对于水生生态系统健康和食品安全至关重要.
  • 需要进一步的研究来解决知识差距,并全面评估污染对生态的影响.