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Updated: Jun 14, 2025

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
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在hGBP3和hGBP3ΔC之间螺旋域的变化导致了明显的寡合体和抗HCV活动

Sowmiya Gupta1, Aunji Pradhan2, Divya Rashmi1

  • 1Protein Engineering Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.

Biochemistry
|August 30, 2024
PubMed
概括

人体酸结合蛋白3 (hGBP3) 通过形成六合体来抑制C型肝炎病毒 (HCV). 它的拼接变体hGBP3ΔC,形成不同的寡合体,并显示抗HCV活性降低,突出显示螺旋域的重要性.

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