综合评估阴道感染使用单个抹布
Barbara Van Der Pol1, Cheri Aycock2, Paula Dixon2
1Division of Infectious Diseases, The University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, USA bvanderp@uab.edu.
Sexually transmitted infections
|August 30, 2024
概括
对性传播感染 (STIs) 进行测试的妇女经常与细菌性阴道炎 (BV) 或 vulvovaginal candidasis (VVC) 共同感染. 用单个样本进行分子检测可以帮助检测这些同时发生的阴道感染.
科学领域:
- 生殖健康 生殖健康
- 传染性疾病 传染性疾病
- 分子诊断学 分子诊断
背景情况:
- 当前的诊断实践经常测试性传播感染 (STIs) 或阴道炎,但不能同时进行两者.
- 这种方法使得重叠感染患者的诊断和治疗变得复杂.
- 阴道炎和性传播感染是影响妇女生殖健康的常见疾病.
研究的目的:
- 为了评估细菌性阴道炎 (BV) 和 vulvovaginal candidiasis (VVC) 共同感染的流行率,在出现症状并进行性传播感染测试的女性中.
- 评估基于分子的多重检测对检测同时发生的阴道感染的有用性.
主要方法:
- 使用了以前测试过性传播感染的症状患者的非识别性阴道样本 (克拉米迪亚甲状腺炎,尼塞利亚淋病,阴道).
- 使用基于分子的BD MAX阴道面板来评估BV和Candida spp. (VVC) 的意思.
- 分析了性病和BV/VVC之间的同时感染率.
主要成果:
- 在有症状的人群中观察到高STI/BV联合感染率 (79.4%).
- STI/VVC同时感染的发生率为27.0%.
- 患有任何测试的性传播感染的女性,同时患有BV感染的几率明显更高 (OR2.86).
结论:
- 接受性传播感染检测的女性表现出高频率的BV联合感染和显著的VVC联合感染的流行率.
- 分子检测为检测同时发生的阴道感染提供了单样样本解决方案.
- 综合测试可以改善阴道感染的诊断和管理.
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