尾腺癌:当前的概念和挑战
1Department of Pathology, Cleveland Clinic, Cleveland Clinic 9500 Euclid Ave, Cleveland, OH 44195, United States.
Seminars in diagnostic pathology
|August 30, 2024
概括
尾腺癌 (ApAC) 诊断是具有挑战性的,因为不断发展的分类,特别是粘膜亚型. 准确的分期和分类对于有效的患者管理和改善这种罕见癌症的结果至关重要.
科学领域:
- 胃肠道病理 胃肠道病理
- 手术瘤学手术瘤学
背景情况:
- 尾腺癌 (ApAC) 是一种罕见的胃肠道恶性瘤,占所有此类瘤的不到1%.
- 目前世界卫生组织的分类将APAC分为粘膜性和非粘膜性亚型,具有不同的组织学特征和预后.
研究的目的:
- 审查目前的尾腺癌的分类和分期.
- 强调与粘膜亚型和腹膜疾病相关的诊断挑战.
主要方法:
- 关于尾腺癌分类和分期的文献综述.
- 专注于粘性和非粘性APAC的组织学特征.
- 讨论诊断挑战及其对患者管理的影响.
主要成果:
- ApAC的命名和分类,特别是粘膜亚型,已经发生了重大变化,导致诊断混乱.
- 粘性ApAC表现出具有不同细胞学和透入侵的粘素池.
- 非性APAC类似于结直肠腺癌,预后较差.
结论:
- 由于不同的治疗方案,准确诊断ApAC,特别是粘膜亚型,至关重要.
- 了解当前的分类和分期对于最佳的患者管理和结果至关重要.
- 在APAC的腹腔膜疾病对外科病理学家提出了重大挑战.
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