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黑巧克力摄入对视网膜血管功能的益处:一个随机,盲目,交叉临床试验
Riccardo Sacconi1,2, Mario Pezzella1,2, Nicolo' Ribarich1,2
1School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Scientific reports
|August 30, 2024
概括
富含黄素的黑巧克力摄入改善了健康个体的视网膜血管功能,通过动态血管分析 (DVA) 测量. 这表明对视网膜健康有潜在的短期益处,需要进一步研究长期影响.
科学领域:
- 眼科医生 眼科 眼科
- 心血管研究研究心血管研究
- 营养科学 营养科学
背景情况:
- 对于富含黄醇的黑巧克力对视网膜血管系统的影响的了解有限.
- 视网膜血管的健康对于保持视力至关重要,并且可以受到各种因素的影响.
研究的目的:
- 研究黑巧克力消费对健康受试者的视网膜血管解剖学和功能性的短期影响.
- 使用先进的成像技术,比较黑巧克力与牛奶巧克力的效果.
主要方法:
- 一个前性的,随机的,盲目的,交叉临床试验,涉及20名健康参与者.
- 使用动态血管分析仪 (DVA) 和光相干断层扫描血管学 (OCT-A) 来评估视网膜血管参数.
- 参与者在交叉设计中食用黑巧克力和牛奶巧克力,在消费前后进行测量.
主要成果:
- 光学连贯断层扫描血管造影 (OCT-A) 显示,在吃黑巧克力或牛奶巧克力后,胆管的 perfusion 密度没有显著变化.
- 动态血管分析仪 (DVA) 显示,在摄入黑巧克力 (p=0.016) 后,在闪刺激后,动脉扩张百分比显著增加,但在摄入牛奶巧克力 (p=0.465) 后没有显著增加.
结论:
- 富含黄素的黑巧克力对视网膜血管具有有益的短期功能作用,这是DVA测量所证明的.
- 这些发现表明黑巧克力在支持视网膜血管健康方面可能发挥作用.
- 建议进行进一步的长期研究,以探索黑巧克力消费对预防视网膜疾病的慢性影响.
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