在老年人中,节奏性血压变化的可靠性
Trevor Lohman1, Isabel J Sible2, Fatemah Shenasa3
1Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Scientific reports
|August 30, 2024
概括
在老年人中,可靠的血压变化 (BPV) 测量至关重要. Beat-to-beat BPV指标,特别是平均真实可变性,在临床使用中显示出高可靠性.
科学领域:
- 心血管生理学心血管生理学
- 老年医学 老年医学
- 生物医学工程 生物医学工程
背景情况:
- 血压变化 (BPV) 是老年人的新兴风险因素,特别是在脑血管和神经退行性疾病中.
- 目前关于BPV指标及其在老年人中可靠的测量方面缺乏共识.
- 非侵入性的连续血压监测为准确的BPV评估提供了潜力.
研究的目的:
- 在老年人中推导和评估各种血压变化 (BPV) 指标的可靠性.
- 使用连续节奏监控来比较不同BPV指标的可靠性.
- 为了评估抗高血压药物使用对BPV指标可靠性的影响.
主要方法:
- 使用连续监测收集了节拍对节拍血压数据.
- 分析了两个连续的7分钟波形,以获得BPV指标.
- 进行了绝对和相对可靠性测试 (类内相关系数 - ICC),比较药物使用者和非使用者.
主要成果:
- 大多数基于序列和分散的BPV指标都表现出良好的测试复试可靠性.
- 对血压不稳定的测量只显示了中等的可靠性.
- 缩和腹缩平均真实变化表现出最高可靠性 (分别为ICC=0.87和0.82),缩平均真实变化在药物组中最可靠.
结论:
- 包括分散和基于序列的测量在内的 Beat-to-beat BPV指标可以通过非侵入性持续监测在老年人中可靠地获得.
- 平均真实变异性成为潜在的优越BPV指标,因为它具有高可靠性,对异常值和低频振荡的敏感性降低.
- 这些发现支持针对老年人群风险分层和风险管理的特定BPV指标的临床实用性.
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