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Updated: Jun 14, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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Published on: November 9, 2020

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工程人造非编码RNA用于向蛋白质降解

Congcong Cao1, Aolin Li2, Chaojie Xu3

  • 1Guangdong Provincial Key Laboratory of Systems Biology and Synthetic Biology for Urogenital Tumors, Shenzhen Institute of Translational Medicine, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Synthetic Biology Research Center, Health Science Center, Shenzhen University, Shenzhen, China.

Nature chemical biology
|August 30, 2024
PubMed
概括

人工长非编码RNAs (alncRNAs) 提供了一种针对蛋白质降解的新方法. 这些alncRNAs有效降解瘤原蛋白,显示癌症治疗开发的希望.

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