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Updated: Jun 14, 2025

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金属蛋白酶PAPP-A对于依赖IGF的冠状细胞分化和组织是必需的

Mette Harboe1, Kasper Kjaer-Sorensen1, Ernst-Martin Füchtbauer1

  • 1Department of Molecular Biology and Genetics, Aarhus University, Universitetsbyen 81, 8000, Aarhus C, Denmark.

Scientific reports
|August 30, 2024
PubMed
概括

金属蛋白酶PAPP-A对于在软骨中释放活性胰岛素类生长因子 (IGF) 是至关重要的. 它的缺失破坏了状细胞的组织,并损害了小鼠和斑马鱼的骨生长.

关键词:
动物模型动物模型冠状细胞是什么意思 冠状细胞是什么意思增长板的增长板是什么意思胰岛素类生长因子 胰岛素类生长因子蛋白质溶解调节的调节

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