对预测胸部手术后呼吸道并发症的CARDOT评分进行外部验证
Tanyong Pipanmekaporn1,2, Pakaros Kitswat3, Prangmalee Leurcharusmee4
1Department of Anesthesiology, Faculty of Medicine, Chiang Mai University, Intavarorote Rd, Muang Chiang Mai District, Chiang Mai, 50200, Thailand. tanyong.p@cmu.ac.th.
BMC anesthesiology
|August 30, 2024
概括
卡多特评分有效预测胸部手术后的呼吸道并发症. 添加中性粒细胞与淋巴细胞比率 (NLR) 显著提高了它的预测准确性,特别是在肺功能测试有限的地方.
科学领域:
- 胸部外科手术 胸部外科手术
- 呼吸道并发症 呼吸道并发症
- 预测得分的预测得分
背景情况:
- 卡多特评分是为了预测胸部手术后的呼吸道并发症而开发的.
- 需要对CARDOT评分进行外部验证.
- 评估术前中性粒细胞与淋巴细胞比率 (NLR) 的预测值也很重要.
研究的目的:
- 在胸部手术后预测呼吸道并发症的CARDOT评分进行外部验证.
- 评估这些并发症的手术前中性粒细胞与淋巴细胞比率 (NLR) 的预测值.
主要方法:
- 对2731名胸部手术患者进行了回顾性队列研究.
- 使用开发 (2006-2012) 和验证 (2015-2021) 数据集对CARDOT评分进行外部验证.
- 使用接收器运行特征 (AuROC) 曲线和校准的接收器运行特征 (AuROC) 曲线下的区域,评估CARDOT得分和NLR性能.
主要成果:
- 在这两组数据中,CARDOT评分表现出了良好的区分能力 (AuROC 0.789和0.758).
- 高NLR (≥4.5) 显著增加呼吸道并发症的风险 (P < 0.001).
- 将CARDOT得分与高NLR结合起来,AuROC提高到0.775,显示出明显更大的歧视 (P = 0.008).
结论:
- 卡多特评分是预测胸部手术后呼吸道并发症的宝贵工具,具有良好的外部验证.
- 将NLR纳入CARDOT评分可以显著提高其预测性能.
- 这种综合方法在资源有限的环境中尤其有用,因为缺乏手术前肺功能测试.
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