Ab-Externo XEN凝支架植入物有效地治疗了耐火性玻璃眼,之前的分流管失败
Anny M S Cheng1,2,3, Shailesh K Gupta1,2, Geetha G Vedula1,4
1Department of Ophthalmology, Broward Health, Fort Lauderdale, FL, USA.
BMC ophthalmology
|August 30, 2024
概括
在先进的玻璃眼病患者中,XEN凝支架有效降低眼内压力 (IOP),这些患者之前有过水性分流失败. 这种手术选择提供了100%的成功率,没有并发症.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 医疗器械 医疗器械
背景情况:
- 晚期玻璃眼需要有效的眼内压力 (IOP) 管理.
- 在耐火性病例中,以前的玻璃眼排水装置 (GDD) 植入可能会失败.
- 对于GDD失败的患者,需要替代性手术选择.
研究的目的:
- 为了评估XEN 45凝支架在眼睛中具有先进的玻璃眼瘤的疗效,这些眼睛以前未能成功植入水性分流器.
- 评估 XEN 支架作为 GDD 失败后的救援程序.
主要方法:
- 在GDD失败后,对6名耐火性玻璃眼患者进行了回顾性审查.
- 使用米托米辛C和切除术进行的XEN支架植入.
- 由IOP≤18mmHg定义的成功,降低了≥25%和降低了药物负担.
主要成果:
- 从32.33 ± 5.99降低到12.67 ± 3.27 mmHg (p < 0.001) 的内脉冲压显著降低.
- 实现了100%的手术成功率,平均随访时间为13.9个月.
- 药物使用显著减少;视敏度和视野保持稳定.
结论:
- 植入XEN凝支架是一种可行的和有效的手术选择,用于在GDD失败后的耐火玻璃眼.
- 该程序显示出高成功率和良好的安全概况.
- 这种方法为患者提供了一个有前途的解决方案,需要在管道分流失败后进一步降低IOP.
相关概念视频
Angle Closure Glaucoma: Treatment
454
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
454
Open Angle Glaucoma: Treatment
408
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
408
Glaucoma: Overview
528
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
528


