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在胚胎移植过程中服用亚泽帕姆的疗效:关于生殖结果的回顾性多中心队列研究

Pedro Brandão¹, Filipa Rafael², Mohamed Saleh²

¹IVIRMA Global Research Alliance, Ginemed Porto, Avenida da Boavista 1243, 4100-130, Porto, Portugal. pbrandao@ginemed.pt.

Journal of assisted reproduction and genetics

|August 31, 2024

概括

在胚胎转移期间服用迪亚泽帕姆并没有显著影响生殖结果,包括活产率. 这表明,在提高试管婴儿成功率方面,迪亚泽巴姆的有效性有限.

科学领域:

生殖医学生殖医学
在体外受精 (IVF)

背景情况:

迪亚泽帕姆有时在胚胎移植过程中使用.
它对试管婴儿成功率的影响仍然是调查的主题.

研究的目的:

为了评估在胚胎移植期间给予迪亚泽帕姆对关键生殖结果的影响.
主要关注活产率,并对怀孕和流产率进行二次分析.

主要方法:

来自葡萄牙和西班牙12家诊所的5607个单个胚胎囊移植的回顾性分析 (2015-2022年).
465例接受过亚泽巴姆的病例与对照组之间的结局比较.

主要成果:

没有观察到群体之间的阳性β-hCG率,临床怀孕率,流产率,宫外怀孕率或活产率的统计学上显著差异.
在非二西巴姆组的活产率为36.3%,而在二西巴姆组的活产率为35.3% (p=0.69).

结论:

在胚胎移植过程中服用迪亚泽帕姆似乎不会影响生殖结果.
这项研究表明,对于提高试管婴儿成功而言,亚泽巴姆的益处有限.

关键词:

迪亚泽帕姆 (Diazepam) 是一种药物.胚胎移植是如何进行胚胎移植的在这个过程中,IVF IVF.活生生的出生率是多少生殖结果的结果.

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