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Updated: Jun 14, 2025

Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma
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在个性化医学中进行临床试验的最佳设计,当响应差异取决于治疗时

Belmiro P M Duarte1,2,3, Anthony C Atkinson4

  • 1Polytechnic Institute of Coimbra, ISEC, Coimbra, Portugal.

Journal of biopharmaceutical statistics
|August 31, 2024
PubMed
概括

这项研究引入了最佳的临床试验设计,将尼曼分配用于个性化医学的概括. 半确定的编程 (SDP) 配方允许计算D-,A-,E-和D-最佳设计,即使在连续试验中具有未知的参数.

关键词:
尼曼的分配额度.最优的设计最优的设计.共同变量 共同变量半确定的编程 半确定的编程顺序分配分配的顺序分配.

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