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在小鼠肝细胞中,Cosmc调节O-甘氨酸扩展

Rajindra P Aryal1, Maxence Noel1, Junwei Zeng1

  • 1Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, CLS 11087 - 3 Blackfan Circle, Boston, MA 02115, United States.

Glycobiology
|August 31, 2024
PubMed
概括

肝细胞通常产生复杂的O-甘氨酸,但在小鼠中删除Cosmc (C1Galt1c1) 会导致它们只产生简单的Tn抗原. 令人惊的是,这种O-糖化变化并没有影响胆固醇代谢或引起可观察到的表型.

关键词:
在宇宙中,宇宙是宇宙.在Tn抗原的抗原.葡萄糖蛋白质 (glycoproteins) 是一种葡萄糖蛋白质.肝细胞 肝细胞 肝细胞肝脏 肝脏 肝脏 肝脏 肝脏 肝脏

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