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在良性甲状腺疾病的手术患者中偶发性甲状腺恶性病变

Priyashma Joshi¹, Jonathan Chang², William H Scola³

¹Weill Cornell Medicine Department of Surgery, New York, New York; University of Miami Leonard M. Miller School of Medicine, Miami, Florida.

The Journal of surgical research

|August 31, 2024

概括

偶然的甲状腺恶性瘤 (ITM) 在为良性甲状腺疾病接受手术的患者中发现了22.9%. 较高的身体质量指数 (BMI) 与增加的ITM率有关,这表明肥胖和甲状腺癌之间存在联系.

科学领域:

内分泌学在内分泌学.
在瘤学瘤学.
病理学病理学病理学

背景情况:

偶发性甲状腺恶性瘤 (ITM) 的发生率有所上升,但导致因素仍然不清楚.
这项研究调查了在没有先前怀疑癌症的情况下患有良性甲状腺疾病 (BTD) 的患者的ITM率.

研究的目的:

为了确定为BTD进行甲状腺切除术的患者的ITM速率.
确定与ITM相关的社会人口统计学和临床因素.

主要方法:

对从2528名患者 (2011-2022) 收集的前性数据的回顾性分析.
包括345名BTD患者,不包括已知甲状腺癌,辐射暴露或可疑的手术前发现的患者.
分析了与人口统计,BMI,瘤大小和侵入性特征的ITM速率.

主要成果:

在22.9%的BTD患者中检测到ITM.
较高的BMI是增加ITM速率 (OR=1.057,P=0.007) 的显著预测因素.
非有毒的多结肠 (multinodular goiter) 的发生率最高 (36.0%);其他因素没有显著的相关性.

结论:

观察到ITM的比报告的更高的率.
高BMI和ITM之间的关联表明,肥胖和甲状腺恶性瘤之间存在潜在联系.
患有BTD和较高BMI的患者可能需要更密切的监测.

关键词:

这就是为什么BMI是BMI.这是偶然的,偶然的.恶性瘤是一种恶性瘤.肥胖问题肥胖问题甲状腺是什么?甲状腺是什么?甲状腺切除术 (thyroidectomy) 是一种切除甲状腺的方法.

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