细胞还原性手术和高热性腹腔内化疗后的急性损伤 - 一项系统性审查
Sohan Lal Solanki1, Bindiya Salunke1, Gauri Gangakhedkar2
1Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
概括
急性损伤 (AKI) 发生在接受细胞削减手术和高温腹腔内化疗 (HIPEC) 的患者中的23.36%. 西斯-HIPEC和先前存在的并发症是关键的风险因素,但术后措施可以减少AKI的发生率.
科学领域:
- 在瘤学瘤学.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 手术瘤学手术瘤学
背景情况:
- 超热内化疗 (HIPEC) 使用毒药物,增加术后急性损伤 (AKI) 的风险.
- 在细胞减小手术 (CRS) 和HIPEC后,关于AKI发病率和风险因素的证据有限且不一致.
- 本系统性审查旨在巩固CRS-HIPEC的背景下关于AKI发病率,相关风险因素和预防策略的当前知识.
结论:
- 在CRS-HIPEC之后,AKI的发生率很大,需要积极的管理策略.
- 术后干预,包括使用硫酸和阿米福斯,表明AKI率显著降低.
- 优化手术前风险因素,管理并发症,确保血液动力学稳定性和维持足够的尿液是缓解AKI风险的关键.
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