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相关概念视频

Physical Properties of Amines01:26

Physical Properties of Amines

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Amines with low molecular weight are usually gaseous at room temperature, while those with high molecular weight are liquid or solids in nature. Usually, low molecular weight amines have a rotten fish-like smell. Diamines typically have a pungent smell. For instance, cadaverine and putrescine, depicted in Figure 1, are two molecules responsible for decaying tissue.
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相关实验视频

Updated: Jun 14, 2025

Source and Route of Pyrrolizidine Alkaloid Contamination in Tea Samples
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来自Anacyclus pyrethrum的类化合物

Hui Chen1, Haji Akber Aisa2

  • 1State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Chinese Academy of Sciences, South Beijing Road 40-1, Urumqi, China; University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Shijingshan District, Beijing, 10004, China.

Phytochemistry
|August 31, 2024
PubMed
概括
此摘要是机器生成的。

从Anacyclus pyrethrum根中分离出了12种新的类化合物. 一些化合物,阿纳西基诺林G和H,通过抑制氧化的产生,显示出潜在的抗炎活性.

关键词:
类化合物是一种类化合物.这就是 Anacyclus pyrethrum.它具有抗炎活性,具有抗炎活性.阿斯特拉属植物 (Asteraceae) 是一个植物.

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Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
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科学领域:

  • 自然产品化学 自然产品化学
  • 药理学是指药理学,即药理学是指药理学.
  • 药用化学 医学化学

背景情况:

  • 亚cyclus pyrethrum (L.) DC. 时间长. 是一种具有传统使用历史的药用植物.
  • 根的化学成分尚未完全阐明.
  • 类化合物是一种多样化的自然产品类别,具有显著的药理作用.

研究的目的:

  • 从Anacyclus pyrethrum根中分离和描述新型化物.
  • 为了研究分离的化合物的潜在抗炎生物活性.

主要方法:

  • 使用色谱技术分离类化合物.
  • 通过全面的光谱分析 (NMR,HRESIMS,UV,IR) 阐明结构.
  • 使用量子化学计算 (ECD,DP4+) 和单晶X射线衍射来确认结构.

主要成果:

  • 确定了12种以前未被描述的化物:八种pyrrolo[3,2-g]isoquinoline化物 (1-6) 和四种pyrrolo[2,3-g]quinoline化物 (7-9).
  • 所有分离的类化合物的结构都被严格确定.
  • 亚纳基基诺林G (7a/7b) 和H (8) 在脂聚糖诱导的RAW 264.7细胞中对氧化的产生表现出抑制作用,IC50值分别为41.4,44.1和31.4μM.

结论:

  • 这项研究成功地从Anacyclus pyrethrum中发现了12种新的类化合物.
  • 亚纳西基诺林G和H具有潜在的抗炎性质,需要进一步研究.