三二甲通过通过AKT/TXNIP信号通路诱导线粒体依赖的亡,产生抗骨肉瘤的作用

Xiangchen Zeng1, Wenkai Chen1, Naichun Yu2

  • 1School of Medicine, Xiamen University, Xiamen, China.

概括

作为一种抗精神病药物,trifluoperazine (TFP) 在治疗骨髓瘤 (OS) 中表现有前途. 它通过增加活性氧物种 (ROS) 和诱导亡来抑制OS细胞的生长和迁移,从而提供了潜在的新疗法.

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