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早期儿童感染对儿童发育和学业成绩的影响:基于人口的研究
Wen-Qiang He1,2, Hannah Catherine Moore3,4, Jessica E Miller5,6
1Child Population and Translational Health Research, Children's Hospital Westmead Clinical School, The University of Sydney, Sydney, New South Wales, Australia wen-qiang.he@sydney.edu.au.
Journal of epidemiology and community health
|August 31, 2024
概括
需要住院治疗的儿童感染与儿童发育和学业表现差异有关. 然而,共同的家庭因素,尤其是社会经济因素,可能会解释这种关联.
科学领域:
- 儿科健康 儿科健康
- 发展心理学 发展心理学
- 公共卫生 公共卫生
背景情况:
- 关于儿童感染与神经发育结果之间的联系存在不一致的发现.
- 了解这种关联对于早期干预和支持至关重要.
研究的目的:
- 调查童年因感染而住院和随后的发育和教育结果之间的关联.
- 探索潜在的混因素,包括共同的家庭影响.
主要方法:
- 在澳大利亚新南威尔士州利用了两个大型,基于人口的记录链接队伍 (2001-2014年出生).
- 评估发育风险和学校成绩 (计数,阅读) 到9岁.
- 采用了考克斯回归,对共变量进行调整,并进行了灵敏度分析 (E值,兄弟分析).
主要成果:
- 与感染相关的住院儿童的发育风险较高,学业成绩较低.
- 经过调整后的分析表明,发育风险 (aHR 1.12) 和学业表现差 (计数 aHR 1.22,读数 aHR 1.16) 的几率增加.
- 敏感性分析表明,在兄弟姐妹分析中,没有测量的混和最小的关联.
结论:
- 与感染相关的住院治疗显示出与儿童发育和学校成绩不良的适度关联.
- 共同的家庭因素,特别是社会经济地位,可能解释了这一关联的很大一部分.
- 这些发现突出了感染,环境和儿童结果的复杂相互作用.
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