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Updated: Jun 14, 2025

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神经母细胞瘤中印记基因的改变甲基化:对预后改进的影响

Medha Suman1, Maja Löfgren1, Susanne Fransson2

  • 1Sahlgrenska Center for Cancer Research, Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Medicinaregatan 1F, 405 30, Gothenburg, Sweden.

Journal of translational medicine
|August 31, 2024
PubMed
概括

在印记区域的异常DNA甲基化在神经母细胞瘤 (NB) 中很常见. 像RB1和NNAT/BLCAP这样的印记基因中的特定甲基化变化可以预测患者的预后,为这种复杂的癌症提供潜在的新临床标志物.

关键词:
副本编号的更改 副本编号的更改通过DNA甲基化.基因组印记是指基因组的印记.神经母细胞瘤的神经母细胞瘤

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