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Updated: Jun 14, 2025

Patch Clamp and Perfusion Techniques for Studying Ion Channels Expressed in Xenopus oocytes
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在CaV1.2激活下对BK通道电流上的4种KCNMA1通道病变的评估

Ria L Dinsdale1, Andrea L Meredith1

  • 1Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA.

Channels (Austin, Tex.)
|September 1, 2024
PubMed
概括

与神经疾病相关的KCNMA1变体显示了改变的BK通道功能. 只有N999S突变在动态条件下持续影响BK电流,突出突变特异性致病性.

关键词:
这就是CACNA1C.在 CaV1.2 中.KCa1.11.1 这是一个很好的例子.激活的通道.道病变是一种通道病变.电压关闭通道的通道.

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