在急诊室的腹痛,恶心和吐患者中使用德罗皮里多尔
Ryan Ernst1, Holden Wagstaff1, Mckayla Smith1
1University of Utah Department of Emergency Medicine, 30 N Mario Capecchi, HELIX Bldg, Salt Lake City, UT 84112, United States of America.
The American journal of emergency medicine
|September 1, 2024
概括
德罗佩里多尔经常用于腹痛,恶心和吐,通常低于FDA警告水平的低剂量. 不良事件很少发生,在本研究中没有观察到重大不良结果.
科学领域:
- 紧急医疗 紧急医疗
- 临床药理学 临床药理学
背景情况:
- 德罗佩里多尔是一种抗和抗精神病药物.
- 它的使用一直受到FDA关于心脏风险的警告.
- 了解当前的使用模式对于患者的安全至关重要.
研究的目的:
- 分析在城市学术医疗中心使用德罗皮多尔的现实世界.
- 专门研究用德罗佩里多尔治疗腹痛,恶心和/或吐的应用.
- 评估这个患者群体中的剂量和不良事件概况.
主要方法:
- 回顾性,观察性,单中心研究.
- 在2019年8月至2020年8月期间提取了德罗皮里多尔管理的数据.
- 包括患有腹痛,恶心或吐的患者.
主要成果:
- 830个患者访问涉及德罗皮里多尔;706个独特的患者.
- 中位剂量为0.625毫克静脉注射,其中71%的人接受了这种剂量.
- 只有2.3%的患者经历了记录的不良事件;没有发生重大不良结果.
结论:
- 在这种情况下,德罗佩里多尔通常用于胃肠道的痛苦.
- 剂量主要保持在2.5毫克IVFDA警告值以下.
- 副作用的发生频率很少,这在这种情况下支持了它的安全概况.
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