运动对患有癌症的成年人疼痛的影响:系统性审查和网络元分析
Jie Wang1, Meiling Lv1, Hongpeng Li2
1School of Nursing (J.W., M.L.), Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Journal of pain and symptom management
|September 1, 2024
概括
综合性炼计划 (CEP) 最好缓解癌症疼痛的强度. 心身运动是有效的减少疼痛干扰. 需要更多的研究来证实这些关于癌症疼痛管理的发现.
科学领域:
- 在瘤学瘤学.
- 疼痛管理 疼痛管理
- 运动科学 运动科学
背景情况:
- 癌症疼痛显著影响患者在身体,心理和社会领域的生活质量.
- 运动被认为是治疗癌症疼痛的有效干预措施,但最佳的运动方式尚不清楚.
研究的目的:
- 为了比较各种运动干预措施在减轻成人患者癌症疼痛的疗效.
- 为了确定最有效的运动类型来管理癌症疼痛的不同方面.
主要方法:
- 进行了随机对照试验 (RCT) 的系统审查和网络元分析.
- 两位独立研究人员使用Cochrane Bias Assessment 2.0进行了文献选,数据提取和质量评估.
- 网络元分析使用了 Stata 15.0 软件.
主要成果:
- 分析了涉及3537名癌症疼痛患者的41项研究,包括有氧运动,持续训练,间歇训练,抵抗力,心身和综合性炼计划 (CEP).
- 与常规护理相比,CEP在减少疼痛强度方面表现出更高的有效性 (SMD = -1.96,95% CI [-3.47, -0.44]),具有97.9%的最佳干预可能性.
- 心身运动在减少疼痛干扰方面最有效 (SMD = -0.65,95% CI [-1.21, -0.09]),在有效性方面排名高 (SUCRA = 83.8%).
结论:
- 综合性炼计划 (CEP) 目前是减少癌症疼痛强度的最有效干预措施.
- 心身运动成为减轻癌症患者疼痛干扰的最佳方法.
- 由于现有研究数量和质量的局限性,需要进一步的高质量研究来验证这些发现.
相关概念视频
01:21Cancer Survival Analysis
334
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
334
02:49Cancer Therapies
7.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K
01:20Exercise and Cardiovascular Response
750
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
750
01:25Analgesia and Pain Management
552
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
552