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2020年健康饮食指数与绝经后妇女口腔微生物组之间的关联
Yihua Yue1, Kathleen M Hovey1, Jean Wactawski-Wende1
1Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, The State University of New York, Buffalo, NY, United States.
The Journal of nutrition
|September 1, 2024
概括
通过2020年健康饮食指数 (HEI-2020) 衡量整体饮食质量,影响了口腔微生物组组成,但没有影响多样性. 然而,特定的饮食成分影响了口腔微生物群的多样性和组成.
科学领域:
- 口腔微生物组研究
- 营养科学 营养科学
- 微生物组和饮食相互作用
背景情况:
- 饮食摄入量与口腔微生物组有关.
- 之前还没有研究过整体饮食质量对口腔微生物群的影响.
研究的目的:
- 检查健康饮食指数-2020 (HEI-2020) 与口腔微生物群多样性和组成之间的关联.
- 从OsteoPerio研究中分析绝经后妇女的这些关联.
主要方法:
- 评估了1175名绝经后妇女的饮食摄入量,使用食物频率问卷计算HEI-2020分数.
- 分析了口腔微生物组的组成和多样性,使用16SrRNA测序从下斑块样本.
- 统计分析包括ANCOVA,PERMANOVA和线性回归模型来评估关联.
主要成果:
- 在HEI-2020总体得分和口腔微生物群α或β多样性之间没有发现显著的关联.
- 较高的HEI-2020分数与特定细菌 (例如,Lautropia,Streptococcus gordonii) 的数量减少以及其他细菌 (例如,Selenomonas sp. ) 的情况.
- 个别HEI-2020组件,如海鲜和添加糖摄入量,与微生物群多样性和组成有关.
结论:
- 2020年健康饮食指数的整体得分与口腔微生物组合有关,但与多样性无关.
- 特定的饮食成分似乎对口腔微生物群的多样性和组成的影响比整体饮食质量更大.
- 研究结果表明,有针对性的饮食干预措施可以有效调节口腔微生物群.
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