在青少年异常性关节炎中疼痛干扰
Rachel L Randell1, Bryce B Reeve2, Elissa R Weitzman3
1R.L. Randell, MD, MSCR, L.E. Schanberg, MD, Department of Pediatrics, Duke University School of Medicine, and Duke Clinical Research Institute, Durham, North Carolina; rachel.randell@duke.edu.
The Journal of rheumatology
|September 1, 2024
概括
疼痛干扰在患有青少年异常性关节炎 (JIA) 的儿童中很常见. 疲劳和行动能力下降与疼痛比疾病活动更为密切相关,这表明了干预的关键领域.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 疼痛管理 疼痛管理
- 患者报告的结果
背景情况:
- 青少年无形性关节炎 (JIA) 显著影响儿童的生活,尽管治疗进展,但疼痛仍然是一个持续的挑战.
- 了解JIA疼痛的多面性质对于确定改善管理和生活质量的目标至关重要.
研究的目的:
- 评估患者报告结果测量信息系统 (PROMIS) 儿童疼痛干扰 (PI) 在患有JIA的儿童中.
- 检查PROMIS PI与该人口中的人口,临床,心理社会和功能变量之间的关系.
主要方法:
- 这是一项涉及355名患有JIA的儿童的横截面,观察性,多中心研究.
- 用描述性统计数据和双变量/多变量分析来评估PI及其相关物质.
主要成果:
- 27%的患有JIA的儿童报告中度至重度PI,而13.3%的儿童每天都会感到疼痛.
- PI与其他疼痛指标相关,并与年龄增加,疾病活性指标和特定治疗 (类固醇,生物药物) 相关.
- 普罗米斯的心理社会和功能指标,特别是疲劳和移动性,与PI有显著的关联,而体力活动则没有.
结论:
- PROMIS PI是患有JIA的儿童的一个普遍问题,受疾病活动的影响,但更强烈的是疲劳和运动限制.
- 普罗米斯PI是一个有价值的,简短的措施,用于例行临床评估在儿科风湿病学.
- 解决疲劳和运动缺陷对于管理JIA儿童高疼痛干扰至关重要.
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