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超阻塞性心肌病的三维心脏建模用于现场患者特定的模拟,以优化隔膜肌切除术

Karin C Smits^1,2,3, Ron G H Speekenbrink¹, Edsko E G Hekman²

¹Department of Cardiothoracic Surgery, Thorax Centrum Twente, Medisch Spectrum Twente, Enschede, The Netherlands.

Innovations (Philadelphia, Pa.)

|September 2, 2024

概括

从心血管磁共振图像中创建的三维心脏模型可以改善超性阻塞性心肌病 (HOCM) 的手术规划. 这些模型增强了外科医生的信心和患者的理解,可能减少并发症.

科学领域:

心脏病学心脏病学
医疗成像医学成像
生物医学工程生物医学工程

背景情况:

超大致阻塞性心肌病 (HOCM) 影响大约每715名年轻成年人中就有1名.
截面肌切除术是对不愿接受医疗治疗的患者的治疗选择.
在HOCM中,复杂的心脏解剖构成了手术期间严重并发症的风险,包括心室隔膜缺陷和心脏阻塞.

研究的目的:

评估基于心血管磁共振 (CMR) 的三维 (3D) 模型在手术前规划和培训中对HOCM隔膜肌切除术的实用性.
评估这些3D模型在减少手术相关并发症和改善患者治疗结果方面的潜力.

主要方法:

使用CMR图像对心脏结构进行细分,并计算左心室壁厚度.
创建了一个3D in silico模型,墙壁厚度超过15毫米被突出显示.
用于手术规划和患者咨询,生成了一个3D打印模型,其中一个充满的部分用于现场模拟和术后质量控制.

主要成果:

在5名HOCM患者中成功创建了手术前的3D in silico和3D打印的心脏模型.
自2020年10月以来,这些模型的使用导致了外科医生的准备能力,信心和决策能力的提高.
患者报告说,他们对自己的病情和即将进行的手术有了更好的了解.

结论:

从CMR数据中获得的3D心脏模型显著优化了手术前规划,手术培训,手术内质量控制和HOCM患者咨询.
建议对更大的患者队伍进行进一步的研究,以量化与手术相关并发症的减少,并评估临床结果.

关键词:

通过3D打印打印3D打印.莫罗程序莫罗程序在现场模拟.磁共振成像技术的使用基于模拟的培训.虚拟手术规划虚拟手术规划

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