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韩国成年人与年龄相关的身体组成变化和代谢模式的分析,使用FDG-PET/CT健康查数据
Chang-Myung Oh1, Ji-In Bang2, Sang Yoon Lee3
1Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Korea.
Diabetes & metabolism journal
|September 2, 2024
概括
与年龄相关的身体组成和葡萄糖代谢变化在韩国男性和女性之间存在显著差异. F-18-fluorodeoxyglucose正子发射断层扫描/计算机断层扫描 (FDG-PET/CT) 揭示了骨矿物质密度,肌肉和脂肪组织的性别特异性模式.
科学领域:
- 放射学 放射学是一门学科.
- 代谢成像 - 代谢成像
- 老年学是一门学科.
背景情况:
- F-18-fluorodeoxyglucose正子发射断层扫描/计算机断层扫描 (FDG-PET/CT) 能够全面评估人体组成和葡萄糖代谢.
- 机会性成像为研究与年龄相关的生理变化提供了有价值的工具.
研究的目的:
- 在韩国人口中调查与年龄相关的身体组成和葡萄糖代谢的变化.
- 用FDG-PET/CT.来确定这些与年龄相关的变化中的性别特异性差异.
主要方法:
- 对278名接受健康查的韩国成年人的FDG-PET/CT扫描,临床病史和实验室数据进行了回顾性分析.
- 骨矿物质密度 (BMD),横截面肌肉面积 (CSMA),肝脏和肌肉霍恩斯菲尔德单位 (HU),皮下脂肪组织 (SAT),腹部内脏脂肪组织 (VAT) 和肌肉葡萄糖代谢的定量评估.
主要成果:
- 在与年龄相关的身体组成变化中观察到显著的性别差异:女性和男性的 BMD 和 CSMA 分别随着年龄的增长而下降.
- 肌肉HU在两性中随着年龄的增长而下降;SAT和VAT显示男性和女性之间的年龄轨迹不同.
- 肌肉葡萄糖代谢与年龄相关的变化因性别而异,女性有正相关性,男性没有相关性.
结论:
- FDG-PET/CT成像显示了与年龄相关的身体组成和葡萄糖代谢变化的明显的性别特异性模式.
- 这些发现强调了在评估与年龄相关的生理变化时考虑性别的重要性.
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