菌对紫外线辐射和可见光的光不活化剂量 - - 收集数据
Anna-Maria Gierke1, Petra Vatter1, Martin Hessling1
1Ulm University of Applied Sciences, Department of Medical Engineering and Mechatronics, Albert-Einstein-Allee 55, D-89081 Ulm (Germany).
AIMS microbiology
|September 2, 2024
概括
这项研究收集了各种紫外线和可见光谱的真菌光不活化数据. 它强调了关键真菌物种的研究缺陷,并建议标准化实验条件,以获得准确的消毒效果.
科学领域:
- 微生物学 微生物学
- 摄影生物学 摄影生物学
- 传染性疾病 传染性疾病
背景情况:
- 菌感染每年造成数百万人的死亡,威胁全球粮食安全.
- 紫外线杀菌辐射 (UVC) 对微生物有效,但对真菌的数据有限.
- 现有的紫外线敏感性数据主要集中在细菌和病毒上,而不是真菌.
研究的目的:
- 为了提供一个全面的概述的真菌光无活化在不同的光谱,包括远紫外线,UVB,UVA,可见光,和传统的254纳米紫外线.
- 编制和标准化有关真菌失活剂量的现有文献数据.
- 确定有关优先级高的真菌物种的研究缺口.
主要方法:
- 在特定的光谱范围内对真菌的光无活化数据进行了文献搜索.
- 获取和标准化的平均日志减少剂量,按真菌物种,频谱,波长和介质进行分类.
- 透明液体介质中的真菌的确定中位数日志减小剂量.
主要成果:
- 编制了过去100年的大约400个数据集,大多数研究使用254纳米紫外线对黑色菌,白菌和白菌进行研究.
- 观察到无活化数据的显著变化,可能是由于不同的实验条件.
- 确定许多世卫组织优先考虑的真菌物种缺乏数据,其中有一半被归类为高或中等优先考虑的真菌物种.
结论:
- 目前关于真菌光灭活的研究是广泛的,但高度可变的.
- 对关键的真菌病原体存在重大知识缺口,阻碍了有效的消毒策略.
- 实验条件的标准化报告,包括传输测量,对于准确和可重复的真菌无活化研究至关重要.
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