疫苗接种作为打击细菌抗菌耐药性的策略的影响
Esteban Zavaleta-Monestel1, Samuel Hasselmyr Hasselmyr2, Jonathan García-Montero3
1Pharmacy, Hospital Clinica Biblica, San Jose, CRI.
Cureus
|September 2, 2024
概括
疫苗接种是通过减少感染和对抗生素的需求来打击抗菌素耐药性 (AMR) 的关键策略. 将疫苗纳入抗菌药物管理计划 (ASP) 改善了患者的治疗结果和公共卫生.
科学领域:
- 全球健康 全球健康
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 抗菌素耐药性 (AMR) 是一个主要的全球健康威胁,增加了发病率,死亡率和医疗保健成本.
- 疫苗接种是预防感染的关键措施,从而减少了抗菌素的使用.
- 抗微生物药物管理计划 (ASP) 旨在优化抗微生物药物的使用和打击耐药性.
研究的目的:
- 评估疫苗在控制AMR中的作用.
- 审查疫苗接种策略的有效性,并将其纳入基于社区的ASP.
- 分析疫苗对减少抗生素依赖和改善患者结果的影响.
主要方法:
- 进行了全面的文献审查.
- 搜索的数据库包括谷歌学者,Scielo和PubMed.
- 选了132篇文章,并包括了13项相关研究 (2005-2024年).
主要成果:
- 疫苗显著减少了对抗生素的依赖,特别是在弱势群体 (老年人,儿童,慢性病患者) 中.
- 结合性肺炎球菌疫苗显示药物耐药性Streptococcus pneumoniae感染的减少.
- 广泛的疫苗接种提供了间接的好处,如群体免疫力和减少耐药菌株的传播.
结论:
- 疫苗接种是对抗AMR的重要组成部分.
- 结合疫苗接种计划的协调ASP可以减轻耐药性感染并优化抗菌剂的使用.
- 提高疫苗覆盖率和接收率对于打击AMR的全球卫生目标至关重要.
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