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周围脏脂肪厚度与2型糖尿病患者进行冠状动脉导管治疗的对比诱导性病有关

Xixiang Tang¹, Jiafu Wang², Yuman Wu³

¹VIP Medical Service Center Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Journal of diabetes research

|September 2, 2024

概括

较厚的周围脂肪 (PRF) 与2型糖尿病患者 (T2DM) 形成对比诱导性脏病 (CIN) 的风险更高有关. 这一发现强调了PRF作为T2DM患者进行心脏手术中CIN发展的关键指标.

科学领域:

腎臟病學 (nephrology) 是一種醫學專業.
心脏病学心脏病学
内分泌学在内分泌学.

背景情况:

脂肪组织的积累与糖尿病并发症有关.
对比诱发性病 (CIN) 是糖尿病患者进行涉及对比介质的手术的显著风险.

研究的目的:

研究不同脂肪组织厚度与2型糖尿病患者中CIN风险之间的关联.
确定特定的脂肪组织储存作为CIN的潜在预测因素.

主要方法:

评估了603名经过皮肤冠状动脉血管学或血管造形术的T2DM患者队列.
对周周脂肪 (PRF),皮下脂肪 (SCF),腹腔内脂肪 (IPF) 和心上脂肪 (ECF) 进行了超声测量.
使用统计分析,包括相关性,ROC和多变量逻辑回归来确定与CIN的关联.

主要成果:

与没有出现CIN的患者相比,患有CIN的患者表现出明显更厚的PRF (13.7毫米 vs 8.9毫米).
PRF厚度与手术后血清肌素变化呈正相关性.
受体操作特征分析表明,PRF是测量脂肪组织中CIN最强的预测因子 (AUC = 0.809).

结论:

在T2DM患者中,周围脂肪厚度独立地与发展对比诱导脏病的风险增加有关.
测量PRF可以作为一个有价值的工具,在这个患者群体中对CIN的风险分层.
向或监测PRF可能与对T2DM患者进行冠状动脉导管治疗的CIN风险的管理有关.

关键词:

对比对比对比的对比对比对比的对比对比对比的对比对比对比对比的对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比对比冠状动脉导管治疗的冠状动脉导管糖尿病糖尿病患者糖尿病患者脏病是一种神经病.周围的脏脂肪周围的脂肪

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