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Updated: Jun 14, 2025

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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对RNA二次结构对Cas13d介导的RNA裂变影响的评估

Mouraya Hussein1,2, Ye Liu1,2, Monique Vink1,2

  • 1Amsterdam UMC, University of Amsterdam, Medical Microbiology and Infection Prevention, Meibergdreef 9, Amsterdam, the Netherlands.

Molecular therapy. Nucleic acids
|September 2, 2024
PubMed
概括

CRISPR-Cas13d系统有效地准病毒RNA,即使是在稳定的结构内. 它的活性只受到极其稳定的RNA发针的影响,因此适用于各种病毒基因组.

关键词:
这就是CRISPR-Cas13d.MT:RNA/DNA编辑 编辑这是一种RNA干扰.结构 RNA 结构 RNA 结构这就是SARS-CoV-2病毒.切割活动的切割活动.基因编辑 基因编辑目标效率效率的目标化

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