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Updated: Jun 14, 2025

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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通过体水相互作用与部位在μOR中介导的信号调制

Rohini S Ople1,2, Nokomis Ramos-Gonzalez1,2, Qiongyu Li3

  • 1Center for Clinical Pharmacology, University of Health Sciences & Pharmacy at St. Louis and Washington University School of Medicine, St. Louis, Missouri 63110, United States.

ACS central science
|September 2, 2024
PubMed
概括

研究人员开发了RO76,一种新型止痛药,通过水分子向mu阿片类受体 (μOR) 部位. 与吗啡相比,这种方法提供了改善的全身活性和减少副作用.

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