轻度认知障碍的边界和热点演变:从2013年到2023年的文献分析分析
Chunying He1,2, Xiaohua Hu1,2, Muren Wang1,2
1Department of Neurology, China Academy of Chinese Medical Sciences Xiyuan Hospital, Beijing, China.
Frontiers in neuroscience
|September 2, 2024
概括
最近关于轻度认知障碍 (MCI) 的研究显示出越来越多的趋势,重点是神经成像和液体生物标志物. 未来的方向包括机器学习,EEG和血液生物标志物,以获得更好的诊断模型.
科学领域:
- 神经学 神经学
- 生物医学信息学 生物医学信息学
- 认知科学 认知科学
背景情况:
- 轻度认知障碍 (MCI) 是一种复杂的综合征,具有显著的异质性,阻碍了研究进展.
- 在MCI定义和进展方面缺乏共识,这在历史上限制了对MCI理解和治疗的进步.
- 需要一个全面的视觉框架来绘制过去十年中MCI研究的演变.
研究的目的:
- 创建过去十年 (2013-2023) 的MCI研究的视觉概述.
- 确定当前的研究热点和轻度认知障碍的新兴趋势.
- 预测MCI最有前途的未来研究方向.
主要方法:
- 从Web of Science (2013年1月至2023年4月) 对6,075篇MCI相关文章进行了图书统计分析.
- 使用CiteSpace和VOSviewer软件可视化研究趋势.
- 分析关键词和共同引用的文献,以确定研究主题和有影响力的作品.
主要成果:
- 出版量显示上升趋势,在2018年之后加速.
- 美国和加利福尼亚大学系统是主要贡献者.
- 目前的研究重点是神经成像,液体生物标志物和预测器;未来的方向包括机器学习,EEG,深度学习和血液生物标志物.
结论:
- 在过去的十年中,MCI研究通过国际合作取得了进展.
- 目前的研究热点集中在诊断生物标记物,如液体标记物和神经成像.
- 预计未来的研究将集中在机器学习驱动的预后/诊断模型和大规模查工具 (EEG,血液生物标志物) 上.
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