复发性上下皮层癌患者的治疗结果
Tamara Dojcinovic1,2, Karin Zibar Tomsic3, Ivana Dora Vodanovic3
1Department of Endocrinology of the Internal medicine clinic, University Clinical Centre of the Republic of Srpska, Banja Luka, Bosnia and Herzegovina.
Endocrine research
|September 2, 2024
概括
复发性上腺皮质癌 (ACC) 治疗结果表明,虽然许多患者面临进展,但不同的疗法可以导致长期存活. 晚年和更短的复发间隔与ACC患者的死亡率增加有关.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 手术瘤学手术瘤学
背景情况:
- 关于复发性上腺皮质癌 (ACC) 患者治疗结果的数据有限.
- 了解这一特定亚群的结果对于改善患者护理至关重要.
研究的目的:
- 评估被诊断患有复发性上腺皮质癌 (ACC) 的患者的治疗结果.
主要方法:
- 追溯性研究包括18名患有复发ENSAT I-III期ACC的患者.
- 患者接受了R0或Rx手术切除.
- 复发后的中位数随访时间为32个月.
主要成果:
- 复发的中位时间为29个月,其中61%患有远程转移.
- 治疗包括重复手术,化疗,米托坦和放射治疗.
- 无进展生存期 (PFS) 的中位数为17个月;整体生存期 (OS) 没有达到.
- 晚年和更短的复发间隔与增加的死亡率有关.
结论:
- 很大一部分患有复发性ACC的患者经历了疾病进展.
- 整合多种治疗方式,在复发性ACC患者中提供了长期生存的潜力.
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