患有炎症性肠道疾病的妇女怀孕后果:英国第三级中心的经验
Ruth Tunney1, Eleanor Liu1, Jimmy K Limdi2,3
1Department of Gastroenterology, Northern Care Alliance NHS Trust, Manchester, UK.
概括
在怀孕之前维持炎症性肠病 (IBD) 的缓解对于有利的妊娠结果至关重要. 在整个怀孕期间最佳的IBD管理可以改善母亲和婴儿的健康.
科学领域:
- 产科和妇科 产科和妇科
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
背景情况:
- 怀孕期间炎症性肠病 (IBD) 的最佳管理与改善母亲和胎儿的结果有关.
- 这项研究检查了英国高等医疗中心在孕妇的IBD管理和结果.
研究的目的:
- 描述孕妇IBD的管理方法.
- 为了评估由IBD复杂的怀孕中母亲和胎儿的结果.
- 评估IBD活动和治疗对怀孕结果的影响.
主要方法:
- 在IBD妇女怀孕的回顾性观察队列研究 (2015-2021).
- 收集关于IBD活动,管理 (怀孕前,怀孕期间,怀孕后) 和母胎结局的数据.
- 统计分析以评估IBD干预,严重程度,治疗和不良妊娠结果之间的关联.
主要成果:
- 分析了130名IBD妇女的怀孕情况;平均产妇年龄为30.5岁.
- 怀孕时活跃的IBD (79.6%) 与早产有关 (p=0.04).
- 孕产妇使用皮质类固醇与低出生体重和新生儿感染有关,特别是在第三个三个月.
结论:
- 在怀孕时临床缓解的IBD妇女经历了有利的怀孕结果.
- 在怀孕前和怀孕后提供高质量的IBD护理至关重要,符合国际指导方针.
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