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Updated: May 12, 2026

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可解释的机器学习预测了tepotinib治疗患者的胀不良事件

Federico Amato1, Rainer Strotmann2, Roberto Castello1

  • 1Swiss Data Science Center (EPFL and ETH Zurich), Lausanne, Switzerland.

Clinical and translational science
|September 2, 2024
PubMed
概括

机器学习模型准确地预测tepotinib治疗患者的风险,这是一种治疗非小细胞肺癌的药物. 这些模型将血清白蛋白和年龄确定为影响发育的关键因素.

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Cytotoxic edema is a form of cerebral edema characterized by intracellular swelling of neurons, astrocytes, and other glial cells. It develops when the mechanisms responsible for maintaining ionic gradients across the cell membrane become impaired. Under normal physiological conditions, the sodium–potassium ATPase actively transports sodium ions out of the cell and potassium ions into the cell, preserving osmotic balance and enabling electrical signaling. This pump requires a continuous supply...