相关实验视频
Updated: Jun 14, 2025

05:16
Sleeve Gastrectomy in Mice using Surgical Clips
Published on: November 14, 2020
6.6K
肥胖患者甲状腺激素的变化与腹手术后的身体组成变化有关
Yu Yan1, Xuehui Chu2, Jing Wang3
1Department of Pancreatic and Metabolic Surgery, Medical School of Southeast University, Nanjing Drum Tower Hospital, Nanjing, Jiangsu 210009, China.
The Journal of clinical endocrinology and metabolism
|September 2, 2024
概括
代谢性减肥手术 (MBS) 在肥胖个体中显著影响甲状腺功能和激素抵抗. 手术后,甲状腺激素和抵抗标志物得到改善,与身体组成的有利变化相关.
科学领域:
- 内分泌学 在内分泌学.
- 代谢手术 代谢手术
- 肥胖医学 肥胖医学
背景情况:
- 肥胖与甲状腺功能改变和甲状腺激素抵抗有关.
- 了解这些关系对于管理代谢健康至关重要.
研究的目的:
- 为了研究代谢/腹部手术 (MBS) 对甲状腺激素 (TH) 水平和肥胖的甲状腺腺症患者的TH抗性的影响.
- 分析这些变化与身体组成的变化之间的相关性.
主要方法:
- 涉及肥胖个体和对照的横截面和纵向研究.
- 在MBS之前和之后评估身体组成 (VFA,体脂百分比,SMM百分比) 和甲状腺功能 (TSH,FT3,TFQI).
- 相关性分析以确定甲状腺功能和身体组成参数之间的关系.
主要成果:
- 肥胖个体表现出高的TSH,ft3和TFQI,这些都在MBS后下降.
- MBS导致内脏脂肪面积 (VFA) 和身体脂肪百分比减少,骨肌肉质量 (SMM) 百分比增加.
- 在手术前,TSH与VFA和身体脂肪百分比正相关,与SMM百分比负相关. 手术后,降低TSH与降低VFA和增加SMM百分比相关.
结论:
- 在肥胖患者中,MBS显著调节甲状腺功能和甲状腺激素抵抗.
- 甲状腺功能的变化和MBS后的耐药性与身体组成的改善密切相关.
相关概念视频
Obesity
416
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
416
Functions of Thyroid Hormones
2.6K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.6K
Synthesis and Regulation of Thyroid Hormones
4.3K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.3K
Hormones and Bone Tissue
2.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.6K
Major Hormones and Their Functions
352
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
352
Anorexia Nervosa
52
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
52

