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作为小分子JAK3抑制剂的cedrol衍生物的设计,合成和活性选

Bingjing Ma1, Hua Li1, Yuan Huang2

  • 1Department of Traditional Chinese Material Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.

Bioorganic chemistry
|September 2, 2024
PubMed
概括

合成了新的cedrol衍生物,以向JAK-STAT途径治疗类风湿性关节炎. 化合物22显示强烈抑制JAK3,为进一步研究炎症性疾病提供了有前途的途径.

关键词:
活动选活动选塞德罗尔 (Cedrol) 是一种这是一种JAK3抑制剂.结构修改是指结构的修改.

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