对一块碎牛肉和豆制肉替代品的合成反应:一个随机对照试验
David D Church1, Katie R Hirsch2, Shiloah A Kviatkovsky1
1Department of Geriatrics, Donald W. Reynolds Institute on Aging, Center for Translational Research in Aging and Longevity, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
The American journal of clinical nutrition
|September 2, 2024
概括
牛肉的消费显著提高了肌肉蛋白质的合成比相当于基于大豆的肉类替代品 (SBMA) 的份额. 然而,一个更大的SBMA服务大小与牛肉匹配.
科学领域:
- 营养科学 营养科学
- 肌肉生理学 肌肉生理学
- 生物化学 生物化学
背景情况:
- 基于大豆的肉类替代品 (SBMA) 越来越受欢迎.
- 与动物肉相比,关于它们对骨肌肉的合成效应的不确定性.
- 需要直接比较肌肉蛋白质合成刺激.
研究的目的:
- 为了比较SBMA与牛肉对骨肌肉蛋白质合成的合成效果.
- 调查SBMA (4司与8司) 与牛肉 (4司) 的剂量反应影响.
主要方法:
- 与健康成年人 (18-40岁) 进行随机对照试验.
- 稳定同位素标记仪方法 (L-[环-2H5]氨酸,[U-13C9-15N]-氨酸,L-[环-2H4]氨酸) 用于测量肌肉蛋白分数合成速率 (FSR).
- 测量全身蛋白质的合成,分解,净平衡和血中必需氨基酸度.
主要成果:
- 与4司的SBMA面包相比,4司的牛肉面包显著增加了肌肉蛋白FSR (P = 0.021).
- 在4司牛肉和8司SBMA (P = 0.454) 之间,肌肉蛋白FSR没有显著差异.
- 最大必需氨基酸度和全身蛋白质合成变化与肌肉FSR变化相关.
结论:
- 牛肉的消费刺激肌肉和全身蛋白质的合成比同等部分的SBMA更有效.
- 一份8司的SBMA显示出与4司的牛肉饼类似的刺激.
- 研究结果表明,SBMA对肌肉蛋白质合成的作用取决于剂量.
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